Structure and function of antifreeze proteins

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Cold survival in freeze-intolerant insects: the structure and function of beta-helical antifreeze proteins.

Antifreeze proteins (AFPs) designate a class of proteins that are able to bind to and inhibit the growth of macromolecular ice. These proteins have been characterized from a variety of organisms. Recently, the structures of AFPs from the spruce budworm (Choristoneura fumiferana) and the yellow mealworm (Tenebrio molitor) have been determined by NMR and X-ray crystallography. Despite nonhomologo...

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Antifreeze proteins

The antifreeze protein (AFP) activity is explained using two models. The first model is using ice binding and the second is using antiice structuralization of water molecules. The description of AFP function using anti-ice structuralization of water molecules is less explored. Therefore, it is of interest to explain AFP function using this model. Protein folding is often described using models ...

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ژورنال

عنوان ژورنال: Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences

سال: 2002

ISSN: 0962-8436,1471-2970

DOI: 10.1098/rstb.2002.1081